Mederma® Gel is a transparent, topical gel that allows patients to treat even the most conspicuous scars with confidence.

The greaseless, pleasant-smelling gel is massaged directly into the scar, so there are no uncomfortable cosmetic pads or dressings. With consistent use, Mederma® Gel can help reduce the appearance of scars resulting from surgeries, injuries, burns and acne.

  • Scar Gel Efficacy
  • Scar Gel Safety
  • Scar Gel Directions for Use
  • Scar Gel Ingredients

Mederma® Gel is clinically proven to reduce the appearance of scars.

In a recent, randomized controlled study1 evaluating 120 identical mid-dermal scars, Mederma® Gel significantly improved the softness, redness, texture and overall appearance of scars in as little as 4 weeks.

Investigator preference for the appearance of Mederma® treated scars at 4, 6 and 10 weeks time was statistically significant (p < 0.001) in softness, redness, texture and overall appearance.

77% of subjects noted moderate to significant improvement overall on scars treated with Mederma® Gel over untreated scars at week 10.

Subjects reported a statistically significant preference for the onion gel-treated (Mederma® Gel) site over the untreated site in terms of redness (P=0.009), texture (P=0.034) and overall appearance (P=0.008) at week 10.

98% of patients completed the study without any study related adverse events or adverse experiences.

Appearance and Texture

In another study, 76% of patients treated with Mederma® Gel reported a significantly less noticeable scar after 8 weeks of use.2 And 84% reported a significantly softer scar.2

Results from Problem Scars

Another study revealed that Mederma® Gel is effective on problem scars. In an open label study, seventy percent (70%) of patients with hypertrophic scarring experienced a substantial improvement in the appearance of their scars after 6 months.4

Mederma® Gel is an excellent adjunct to keloid shave.5 Mederma® Gel used in conjunction with a keloid shave provides good cosmesis, minimal discomfort, and decreased chance of keloid recurrence. The Mederma® Gel Ishave combination is a simpler, less expensive scar treatment than steroid injections.

When used as directed, Mederma® Gel is safe enough for any patient with a scar — from children over 6 months to the elderly.

However, some people may be sensitive to its ingredients. If patients experience persistent itching, swelling or scar discoloration, they should stop using Mederma® Gel immediately.

Mederma® Advanced Gel

Upon application Mederma® Advanced gel will restore moisture to scars and should be evenly applied and gently rubbed into the scar once a day for 8 weeks on new scars, and once a day for 3-6 months on old scars. Apply Mederma® Advanced Gel as soon as your wound has closed.

Mederma® Gel is formulated with our proprietary botanical extract, Cepalin®, and is a greaseless, pleasant-smelling therapy clinically proven to reduce the appearance of scars.

Mederma® Advanced Gel

Aqua, PEG-200, Alcohol, Xanthan Gum, Allium Cepa (Onion) Bulb Extract, Lecithin, Methylparaben, Sorbic Acid, Panthenol, Sodium Hyaluronate, Parfum.

Mederma® Original Scar Gel


  1. Draelos Z., The ability of onion extract gel to improve the cosmetic appearance of postsurgical scars, Cosmetic Dermatology, June 2008.
  2. Clark LF et al. A prospective double-blinded study of Mederma® Skin Care vs. placebo for post-traumatic scar reduction. Cosmetic Dermatology, March 1999.
  3. Baumann LS, Spencer J. The effects of topical vitamin E on the cosmetic appearance of scars. Dermatological Surgery, April 1999.
  4. Leyden JJ, Grove GL. Data on file, Merz Pharmaceuticals, June 1997.
  5. Goldman E. Onion extract a good adjunct to keloid shave [Review of study by Dr. LE Millikan]. Skin & Allergy News, March 1999.